ABSTRACT
Introduction: Ultraviolet B (UVB) radiation exposures induced toxicity and generate oxidative stress on liver tissue and their alternative effect on biochemical process. Curcumin (Cur) and ascorbic acid (AA) act as a good antioxidant and shown the protective effect on animal tissue. Materials and Methods: Twenty-four adult healthy female Wistar rats weighing 130–150 g were used. It is divided into four groups, the 1st group considers as control, the 2nd group considers as UVB treated, the 3rd group considers as UVB + Cur group, and the last 4th group considers as UVB + AA, exposure of radiation for 15 days. Results: We found that UVB radiation shown on the female Wistar rat alteration on the animal body weight, liver weight, lipid peroxide, superoxide dismutase, and glutathione as compared to the control group. Conclusion: It is concluded that UVB radiation shows the harmful effect on female Wistar rat and little preventive effect of Cur and AA.